Delmitide

Delmitide has been in phase II clinical trials for the treatment of crohn's disease and ulcerative colitis. This compound was originally discovered by Genzyme, then licensed to Procter & Gamble in 2004. However, no recent development has been reported.

General Information

Update Date:2016-01-18

Drug Name:
Delmitide
Research Code:
Allotrap-1258; Rationally Designed Peptide 58; RDP-1258; RDP-58
Trade Name:
MOA:
IL-12 production inhibitor;TNF-alpha production inhibitor; IFN-gamma production inhibitor
Indication:
Crohn's disease; Ulcerative colitis
Status:
Phase II (Pending)
Company:
Genzyme (Originator) , Procter & Gamble
Sales:
ATC Code:
Chemical Structure

Update Date:2016-01-18

Molecular Weight 1228.57
Formula C59H105N17O11
CAS No. 287096-87-1 (Delmitide);
Chemical Name D-Tyrosinamide, D-arginyl-D-norleucyl-D-norleucyl-D-norleucyl-D-arginyl-D-norleucyl-D-norleucyl-D-norleucylglycy
Delmitide (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
1228.57 22 28 49 475 3.770±0.932
*:Calculated by ACD/Labs software V11.02.