R-228060

R-228060 is in phase III clinical trials for the treatment of narcolepsy.

It was originally developed by SK Biopharmaceuticals. And Jazz Pharmaceuticals finally acquired the compound in 2014.

General Information

Update Date:2016-02-02

Drug Name:
R-228060
Research Code:
JZP-110; ADX-N05; ARL-N05; R-228060; SKL-N05; YKP-10A
Trade Name:
MOA:
Unknown
Indication:
Narcolepsy
Status:
Phase III (Active)
Company:
SK (Originator) , Jazz Pharmaceuticals
Sales:
ATC Code:
Chemical Structure

Update Date:2016-01-22

Molecular Weight 230.69
Formula C10H14N2O2 ● HCl
CAS No. 178429-62-4;
561069-23-6;
Chemical Name Benzenepropanol, b-amino-, 1-carbamate, (bR)-,hydrochloride (1:1)
MW HD HA FRB* PSA* cLogP*
194.23 4 4 6 78.3 0.725±0.324
*:Calculated by ACD/Labs software V11.02.
Synthesis & Impurities

Update Date:2016-01-05


1. WO9607637A1.


1. US2005080268A1

Impurity database is being updated!