SA-13353

SA-13353 has been in phase II clinical trials for the treatment of diabetic macular edema and rheumatoid arthritis. However, this research has been discontinued.

The compound was originally developed by Santen Pharmaceutical, licensed to Ayumi Pharmaceutical in 2015.

General Information

Update Date:2016-04-25

Drug Name:
SA-13353
Research Code:
DE-096; SA-13353
Trade Name:
MOA:
Tumor necrosis factor (TNF)-alpha inhibitor
Indication:
Diabetic macular edema; Rheumatoid arthritis (RA)
Status:
Phase Ⅱ (Discontinued)
Company:
Santen (Originator) , Ayumi
Sales:
ATC Code:
Chemical Structure

Update Date:2015-12-31

Molecular Weight 411.62
Formula C26H41N3O
CAS No. 379262-36-9 (SA-13353);
Chemical Name Urea, N-pentyl-N'-[3-(4-pyridinyl)propyl]-N-(2-tricyclo[3.3.1.13,7]dec-1-ylethyl)-
SA-13353 (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
411.62 1 4 11 45.2 6.781±0.407
*:Calculated by ACD/Labs software V11.02.