Lexanopadol Hemicitrate

Lexanopadol hemicitrate is in phase II clinical trials for the treatment of pain. However there is no recent development reported. 

The compound was originally developed by Gruenenthal, licensed to Forest (acquired by Actavis in 2014) in 2010.

General Information

Update Date:2016-02-01

Drug Name:
Lexanopadol Hemicitrate
Research Code:
GRT-13106G; GRT-6006
Trade Name:
MOA:
Opioid receptor agonist
Indication:
Pain
Status:
Phase II (Pending)
Company:
Grunenthal (Originator) , Actavis
Sales:
ATC Code:
Chemical Structure

Update Date:2016-02-01

Molecular Weight 460.52
Formula C23H25FN2O • 1/2C6H8O7
CAS No. 1357348-09-4 (Lexanopadol);
Chemical Name
Lexanopadol (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
364.46 2 3 2 37.0 4.332±0.575
*:Calculated by ACD/Labs software V11.02.