Zelandopam hydrochloride

Zelandopam hydrochloride has been in phase II clinical trials  for the treatment of heart failure and hypertension. However, no recent development has been reported.

The compound was originally developed by Yamanouchi (now Astellas), and then licensed to Mochida.

General Information

Update Date:2016-01-26

Drug Name:
Zelandopam hydrochloride
Research Code:
MYD-37; YM-435
Trade Name:
MOA:
Dopamine D1 agonist
Indication:
Heart failure; Hypertension
Status:
Phase II (Pending)
Company:
Astellas (Originator) , Mochida
Sales:
ATC Code:
Chemical Structure

Update Date:2016-01-26

Molecular Weight 327.76
Formula C15H15NO4 • HCl • H2O
CAS No. 139233-53-7 (Zelandopam (Free));
Chemical Name
Zelandopam (Free) (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
273.28 5 5 5 93.0 0.851±0.453
*:Calculated by ACD/Labs software V11.02.