Naluzotan Hydrochloride

Naluzotan Hydrochloride is in phase II clinicals for the treatment of epilepsy/seizures. This compound was originally discovered by Epix Pharmaceuticals,and now is being co-developed by Proximagen in collaboration with National Institute of Neurological Disorders and Stroke (NINDS) under a collaboration research and development agreement (CRADA).

General Information

Update Date:2016-02-04

Drug Name:
Naluzotan Hydrochloride
Research Code:
PRX-00023
Trade Name:
MOA:
5-HT1A receptor agonist
Indication:
Epilepsy/Seizures
Status:
Phase II (Active)
Company:
Epix (Originator) , National Institute of Neurological Disorders and Stroke,Upsher Smith Laboratories
Sales:
ATC Code:
Chemical Structure

Update Date:2016-02-04

Molecular Weight 523.56
Formula C23H38N4O3S • 2HCl
CAS No. 740873-06-7 (Naluzotan);
740873-07-8 (Naluzotan Dihydrochloride);
Chemical Name Acetamide, N-[3-[4-[4-[[(cyclohexylmethyl)sulfonyl]amino]butyl]-1-piperazinyl]phenyl]-, hydrochloride (1:2)
Naluzotan (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
450.64 2 7 9 90.1 2.731±0.653
*:Calculated by ACD/Labs software V11.02.