Tedatioxetine

Tedatioxetine is in phase I clinical trials for the treatment of major depression, generalized anxiety disorder.

Tedatioxetine had been in phase II clinical trials for the treatment of major depression. However, Lundbeck decided to discontinue this indication for strategic reasons in 2014

The compound was originally developed by Lundbeck. Then it was co-developed by Lundbeck and Takeda in the U.S. and Japan.

General Information

Update Date:2016-04-11

Drug Name:
Tedatioxetine
Research Code:
Lu-AA-24530
Trade Name:
MOA:
Multimodal anti-depressant
Indication:
Major depressive disorder (MDD); Generalised anxiety disorder (GAD)
Status:
Phase Ⅱ (Discontinued)
Company:
Takeda (Originator) , Lundbeck
Sales:
ATC Code:
Chemical Structure

Update Date:2015-08-24

Molecular Weight 364.34
Formula C18H21NS●BrH
CAS No. 960151-65-9 (Tedatioxetine hydrobromide);
508233-95-2 (Tedatioxetine);
Chemical Name Piperidine, 4-[2-[(4-methylphenyl)thio]phenyl]-, hydrobromide (1:1)
Tedatioxetine hydrobromide (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
283.43 1 1 3 37.3 3.481±0.361
*:Calculated by ACD/Labs software V11.02.