OC-459

OC-459 is in phase II clinical trials for the treatment of allergic rhinitis, asthma, allergic conjunctivitis, atopic dermatitis.

The compound was co-developed by Oxagen Ltd and Atopix Therapeutics.

General Information

Update Date:2015-10-12

Drug Name:
OC-459
Research Code:
OC-459; OC-000459
Trade Name:
MOA:
CRTH2 receptor antagonist
Indication:
Allergic rhinitis (AR); Asthma; Allergic conjunctivitis; Atopic dermatitis
Status:
Phase II (Active)
Company:
Oxagen (Originator), Atopix Therapeutics (Originator)
Sales:
ATC Code:
Chemical Structure

Update Date:2015-10-12

Molecular Weight 348.37
Formula C21H17FN2O2
CAS No. 851723-84-7 (OC000459);
Chemical Name 1H-Indole-1-acetic acid, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-
OC000459 (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
348.37 1 4 4 55.1 3.603±0.577
*:Calculated by ACD/Labs software V11.02.