Eflucimibe

Eflucimibe has been in phase II clinical trials for the treatment of atherosclerosis and hyperlipidemia. However, this research has been discontinued.

The compound was codeveloped by Pierre Fabre and Lilly.

General Information

Update Date:2016-04-26

Drug Name:
Eflucimibe
Research Code:
F-12511; L-0081
Trade Name:
MOA:
ACAT inhibitor
Indication:
Atherosclerosis; Hyperlipidemia
Status:
Phase Ⅱ (Discontinued)
Company:
Pierre Fabre (Originator) , Lilly
Sales:
ATC Code:
Chemical Structure

Update Date:2016-01-06

Molecular Weight 469.72
Formula C29H43NO2S
CAS No. 202340-45-2 (Eflucimibe);
Chemical Name Benzeneacetamide, a-(dodecylthio)-N-(4-hydroxy-2,3,5-trimethylphenyl)-, (aS)-
Eflucimibe (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
469.72 2 3 16 74.6 7.948±0.519
*:Calculated by ACD/Labs software V11.02.