Dasantafil

Dasantafil had been in phase II clinical trials for the treatment of erectile dysfuntion. However, there is no report for this compound recently.

Index：

General Information

Update Date：2016-03-01

Drug Name：
Dasantafil
Research Code：
SCH-446132
Trade Name：
MOA：
Phosphodiesterase PDE5A inhibitor
Indication：
Erectile dysfunction (ED)
Status：
Phase II (Pending)
Company：
Merck Sharp & Dohme (Originator)
Sales：
ATC Code：
Chemical Structure

Update Date：2015-10-13

Molecular Weight 522.39
Formula C22H28BrN5O5
CAS No. 569351-91-3 (Dasantafil);
Chemical Name 1H-Purine-2,6-dione, 7-[(3-bromo-4-methoxyphenyl)methyl]-1-ethyl-3,7-dihydro-8-[[(1R,2R)-2-hydroxycyclopentyl]amino]-3-(2-hydroxyethyl)-
Dasantafil （Free Acid/Base）Parameters：
MW HD HA FRB* PSA* cLogP*
522.39 3 10 9 120 2.925±0.821
*：Calculated by ACD/Labs software V11.02.