PPI-1019

PPI-1019 had been in phase I/II clinical trials by Praecis Pharmaceuticals (acquired by GlaxoSmithKline in 2007) for the treatment of Alzheimer's disease(AD). However, this study had been discontinued.

General Information

Update Date:2016-04-29

Drug Name:
PPI-1019
Research Code:
PPI-1019; Apan
Trade Name:
MOA:
Amyloid beta-protein inhibitor
Indication:
Alzheimer's disease (AD)
Status:
Phase Ⅱ (Discontinued)
Company:
GlaxoSmithKline (Originator)
Sales:
ATC Code:
Chemical Structure

Update Date:2015-11-18

Molecular Weight 650.85
Formula C36H54N6O5
CAS No. 290828-45-4 (PPI-1019);
Chemical Name D-Leucinamide, N-methyl-D-leucyl-D-valyl-D-phenylalanyl-D-phenylalanyl-
PPI-1019 (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
650.85 7 11 19 172 4.509±0.807
*:Calculated by ACD/Labs software V11.02.