Ipamorelin

Ipamorelin has been in phase II clinical trials for the treatment of postoperative ileus and gastrointestinal dysmotility. However, no recent development has been reported. 

The compound was discovered by Novo Nordisk, and in 2006 licensed to Sapphire Therapeutics (acquired by Helsinn Therapeutics in 2009).

General Information

Update Date:2016-01-19

Drug Name:
Ipamorelin
Research Code:
NNC-26-0161
Trade Name:
MOA:
Growth hormone secretagogues receptor agonists
Indication:
Postoperative ileus; Gastrointestinal motility disorders
Status:
Phase II (Pending)
Company:
Novo Nordisk (Originator) , Helsinn
Sales:
ATC Code:
Chemical Structure

Update Date:2016-01-19

Molecular Weight 711.85
Formula C38H49N9O5
CAS No. 170851-70-4 (Ipamorelin);
Chemical Name L-Lysinamide, 2-methylalanyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-D-phenylalanyl-
Ipamorelin (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
711.85 11 14 21 240 2.196±0.861
*:Calculated by ACD/Labs software V11.02.